METHYL 2-OXO-1-PYRROLIDINEACETATE
2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER
CAS: 59776-88-4
Molecular Formula: C7H11NO3
METHYL 2-OXO-1-PYRROLIDINEACETATE - Names and Identifiers
METHYL 2-OXO-1-PYRROLIDINEACETATE - Physico-chemical Properties
| Molecular Formula | C7H11NO3 |
| Molar Mass | 157.17 |
| Density | 1.131 g/mL at 25 °C (lit.) |
| Boling Point | 144-148℃ (16 Torr) |
| Flash Point | >230 °F |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Appearance | Oil |
| Color | Colourless |
| pKa | -1.01±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.472(lit.) |
| MDL | MFCD00003198 |
METHYL 2-OXO-1-PYRROLIDINEACETATE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
METHYL 2-OXO-1-PYRROLIDINEACETATE - Upstream Downstream Industry
METHYL 2-OXO-1-PYRROLIDINEACETATE - Introduction
ACID METHYL ESTER is an organic compound with the chemical formula C7H11NO3. It is a colorless liquid with a special smell. The following is detailed information about its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in organic solvents, insoluble in water
-Melting point: About -15 ° C
-Boiling point: about 145-155 ° C
-Density: approx. 1.12 g/mL
-Refractive index: about 1.463
Use:
ACID METHYL ESTER is often used as a reagent or experimental intermediate in organic synthesis. It can be used for the synthesis of pyrroline, β-lactam, furans and other organic compounds. In addition, it can also be used as a pharmaceutical intermediate for the synthesis of drugs or drug precursors.
Method:
The preparation method of ACID METHYL ESTER adopts esterification reaction. A common preparation method is to react 2-oxo-1-pyrrolidine acetic acid with methanol, add an acid catalyst, and heat the reaction to generate the target product.
Safety Information:
-acrylic METHYL ESTER may be irritating to the human body, causing eye, skin and respiratory tract irritation. Wear appropriate personal protective equipment, such as gloves, goggles and respirators.
-Avoid contact with fire or high temperature environment, because it is flammable.
-Storage should be kept away from fire and oxidant, and the storage temperature should be less than 30°C under inert gas.
-When using, pay attention to prevent inhalation, swallowing or contact with the skin, and clean the contaminated area in time when necessary.
Please note that the use and handling of chemicals should follow proper laboratory safety practices and personal protective measures. Before using any chemical, be sure to carefully read and follow the relevant safety data sheet (SDS) of the chemical.
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in organic solvents, insoluble in water
-Melting point: About -15 ° C
-Boiling point: about 145-155 ° C
-Density: approx. 1.12 g/mL
-Refractive index: about 1.463
Use:
ACID METHYL ESTER is often used as a reagent or experimental intermediate in organic synthesis. It can be used for the synthesis of pyrroline, β-lactam, furans and other organic compounds. In addition, it can also be used as a pharmaceutical intermediate for the synthesis of drugs or drug precursors.
Method:
The preparation method of ACID METHYL ESTER adopts esterification reaction. A common preparation method is to react 2-oxo-1-pyrrolidine acetic acid with methanol, add an acid catalyst, and heat the reaction to generate the target product.
Safety Information:
-acrylic METHYL ESTER may be irritating to the human body, causing eye, skin and respiratory tract irritation. Wear appropriate personal protective equipment, such as gloves, goggles and respirators.
-Avoid contact with fire or high temperature environment, because it is flammable.
-Storage should be kept away from fire and oxidant, and the storage temperature should be less than 30°C under inert gas.
-When using, pay attention to prevent inhalation, swallowing or contact with the skin, and clean the contaminated area in time when necessary.
Please note that the use and handling of chemicals should follow proper laboratory safety practices and personal protective measures. Before using any chemical, be sure to carefully read and follow the relevant safety data sheet (SDS) of the chemical.
Last Update：2024-04-09 15:18:03
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View History
METHYL 2-OXO-1-PYRROLIDINEACETATE
Calcium nitrite
RET激酶抑制剂(AST 487)
6,6-DIFLUOROSPIRO[3.3]HEPTAN-2-AMINEHYDROCHLORIDE
QUINOLINE-5-CARBOTHIOIC ACID AMIDE
Calcium nitrite
RET激酶抑制剂(AST 487)
6,6-DIFLUOROSPIRO[3.3]HEPTAN-2-AMINEHYDROCHLORIDE
QUINOLINE-5-CARBOTHIOIC ACID AMIDE
Raw Materials for METHYL 2-OXO-1-PYRROLIDINEACETATE
Acetic acid, 2-[(3,4-dihydro-2H-pyrrol-5-yl)oxy]-, methyl ester
1-TRIMETHYLSILYL-2-PYRROLIDINONE
METHYL DIAZOACETATE
Methyl bromoacetate
2-Pyrrolidinone
1-TRIMETHYLSILYL-2-PYRROLIDINONE
METHYL DIAZOACETATE
Methyl bromoacetate
2-Pyrrolidinone
Downstream Products for METHYL 2-OXO-1-PYRROLIDINEACETATE